The rise of GLP-1 receptor agonists has revolutionized obesity treatment, offering unprecedented weight loss outcomes. However, clinical data highlight a major challenge: low patient adherence and high discontinuation rates, leading to suboptimal treatment effectiveness and increased healthcare costs.
In this webinar, we will explore: The societal burden of obesity and its economic implications
The real-world persistence of GLP-1 treatments and reasons for discontinuation
How alternative dosing regimens could maintain efficacy while reducing costs
The impact of patient adherence on long-term treatment success
We will discuss the latest clinical trial insights, economic evaluations, and patient behavior trends, examining whether a personalized, optimized dosing strategy could improve treatment outcomes.
Join us for a thought-provoking session featuring expert perspectives on how to make GLP-1 treatments more sustainable and effective for both patients and healthcare systems.
Mickaël Hiligsmann is an Associate Professor in Health Economics and Health Technology Assessment at the Department of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, the Netherlands.
With nearly 20 years of research experience, he specializes in health economic evaluations, including cost-effectiveness analyses, decision-analytic modeling, healthcare valuation, and medication adherence. His work spans various disease areas, with a particular focus on prevention.
He has supervised approximately 25 PhD students as a co-promotor and serves as a senior lecturer in Health Technology Assessment and health economics courses. He has authored around 325 peer-reviewed articles.
Currently, he is the Chair-elect of the ISPOR Special Interest Group on Medication Adherence and Persistence and serves as Editor-in-Chief of Expert Review of Pharmacoeconomic & Outcomes Research.
Sean Lawley is an Associate Professor of Mathematics at the University of Utah. His research uses mathematics to answer questions in physiology and medicine. His work on medication nonadherence has addressed questions such as (i) what patients should do if they miss a dose, (ii) how clinicians can design dosing regimens to mitigate nonadherence, and (iii) how efficacy depends on adherence. He has also studied ovarian aging, menopause timing, and stochastic search. He received a PhD in Mathematics from Duke University in 2014 and a BS in Computational Finance from Carnegie Mellon University in 2009.
Bernard Vrijens pioneered a research program focused on a simple but robust taxonomy of common dosing errors, along with exploring optimal measurement-guided medication management that can drive adherence and maintain long-term persistence. With over 100 peer-reviewed scientific papers and six patents to his name, Dr. Vrijens is also a founding member of the International Society for Medication Adherence (ESPACOMP) and an active contributor to several EU and US-funded collaborative projects, cementing his status as a leading authority in the field.
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